SARS-CoV-2-specific T cell immune response in mRNA vaccinated mice after stimulation of WT RBD-specific peptide pools.

(A-D) FCM analysis results show the percentages of CD4+ Tem cells secreting (A) TNF-α, (B) IL-2, (C) IFN-γ, and (D) IL-4. (E-H) FCM analysis results show the percentages of CD8+ Tem cells secreting (E) TNF-α, (F) IL-2, (G) IFN-γ, and (H) IL-4. S...

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Main Author:	Zuxin Liang (16414112) (author)
Other Authors:	Chunhui Li (501186) (author), Xiaohua Gong (261560) (author), Guoguo Ye (9707977) (author), Yushan Jiang (16414109) (author), Huiping Shi (3135015) (author), Abid Hussain (375044) (author), Mengyuan Zhao (412470) (author), Mengjun Li (4750566) (author), Yuxin Tian (442502) (author), Wei Zhao (14321) (author), Yang Yang (45629) (author), Yuanyu Huang (1422829) (author), Chenguang Shen (11560967) (author), Minghui Yang (588064) (author)
Published:	2024
Subjects:	Biophysics Microbiology Molecular Biology Evolutionary Biology Immunology Infectious Diseases Virology Computational Biology xlink "> emerging receptor binding domain providing valuable insights mediated immune responses elicit antibodies capable antibody binding changes spectrum neutralizing efficacy engineered glycosylation modifications conserved antibody response 2 rbd vaccines neutralizing sars wide range type rbd thereby exposing targeted approach related coronaviruses prone sites mice challenged messenger rna decisive factor coronaviruses remain conferred protection cellular immunity 2 variants 16 strain
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SARS-CoV-2-specific T cell immune response in mRNA vaccinated mice after stimulation of WT RBD-specific peptide pools.

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