Pharmacology in silico: rMS-induced LTP depends on dendritic sodium and calcium through voltage-gated calcium channels, as well as synaptic NMDA channels.

Pharmacology in silico: rMS-induced LTP depends on dendritic sodium and calcium through voltage-gated calcium channels, as well as synaptic NMDA channels.

<p><i>(a)</i>: Schematic of electric field for all panels in this figure. Electric field vector direction shown by E. In addition, all regions of the CA1 pyramidal cell are synaptically stimulated because we assume that electric field not only depolarises the postsynaptic neuron bu...

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Bibliografische gegevens
Hoofdauteur: Nicholas Hananeia (22683665) (author)
Andere auteurs: Christian Ebner (1276467) (author), Christos Galanis (15210328) (author), Hermann Cuntz (32618) (author), Alexander Opitz (295799) (author), Andreas Vlachos (47497) (author), Peter Jedlicka (179938) (author)
Gepubliceerd in: 2025
Onderwerpen:
Medicine
Cell Biology
Neuroscience
Physiology
Space Science
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
results :</ b
previous experimental studies
objective :</ b
methods :</ b
like cellular effects
conclusion :</ b
background :</ b
strongly distance dependent
scale modeling tools
repetitive magnetic stimulation
biophysical neuronal models
1 hz protocols
successfully modelled plasticity
induced synaptic plasticity
dependent plasticity model
plasticity model
dependent spatio
scale modelling
burst stimulation
5 hz
plasticity amplitude
distal plasticity
term potentiation
term changes
temporal resolution
temporal changes
rms ).
previously established
parameter screening
neurons stimulated
neuronal dendrites
modelling framework
mechanisms behind
low sensitivity
high spatio
fully understood
detailed prediction
dendritic spikes
comprehensive module
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