Purification of CD163/Hp(1–1)Hb and CD163/HpSPHb complexes.

(A) Size-exclusion chromatogram and (B) corresponding SDS–PAGE analysis of the purified CD163/Hp(1–1)Hb complex. The fraction highlighted in the chromatogram was analyzed in the SDS–PAGE reducing gel showing each component of the complex. (C)&l...

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Tác giả chính:	Ching-Shin Huang (21703202) (author)
Tác giả khác:	Hui Wang (30400) (author), Joshua B. R. White (14254170) (author), Oksana Degtjarik (2810629) (author), Cindy Huynh (2697772) (author), Kristoffer Brannstrom (21703205) (author), Mark T. Horn (21703208) (author), Stephen P. Muench (236881) (author), William S. Somers (2659714) (author), Javier Chaparro-Riggers (15013755) (author), Laura Lin (2272402) (author), Lidia Mosyak (1635880) (author)
Được phát hành:	2025
Những chủ đề:	Biophysics Biochemistry Cell Biology Molecular Biology Pharmacology Immunology Cancer Space Science Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified renal tissues due haptoglobin &# 8211 circulating haptoglobin acts bound receptor assemblies electron microscopy structures composite binding site 1 binding stoichiometry cd163 scavenger receptor cd163 remains unclear molecular mechanism underlying hemoglobin clearance mechanism ligand binding site molecular mechanism structures reveal human cd163 cd163 functions unliganded state study elucidates structural elucidation primary defense oxidative nature one protomer mostly well free hemoglobin damage vascular autoinhibitory configuration also form
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Purification of CD163/Hp(1–1)Hb and CD163/HpSPHb complexes.

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