Table_2_Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors.XLSX

Table_2_Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors.XLSX

<p>Knockdown or gene disruption of the ubiquitously expressed cell surface receptor CD47 protects non-malignant cells from genotoxic stress caused by ionizing radiation or cytotoxic chemotherapy but sensitizes tumors in an immune competent host to genotoxic stress. The selective radioprotectio...

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Bibliographic Details
Main Author: Sukhbir Kaur (324270) (author)
Other Authors: Anthony L. Schwartz (7449812) (author), David G. Jordan (7449815) (author), David R. Soto-Pantoja (7449818) (author), Bethany Kuo (7449821) (author), Abdel G. Elkahloun (7449824) (author), Lesley Mathews Griner (2851961) (author), Craig J. Thomas (17880) (author), Marc Ferrer (191300) (author), Anish Thomas (2832914) (author), Sai-Wen Tang (7449827) (author), Vinodh N. Rajapakse (7449830) (author), Yves Pommier (11158) (author), David D. Roberts (122430) (author)
Published: 2019
Subjects:
Cancer
Cancer Cell Biology
Cancer Diagnosis
Cancer Genetics
Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
Chemotherapy
Haematological Tumours
Molecular Targets
Radiation Therapy
Solid Tumours
Oncology and Carcinogenesis not elsewhere classified
radioresistance
epigenetics
CD47
thrombospondin-1
DNA damage response
schlafen-11
prostate cancer
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