Presentation 1_Human interleukin-4-dependent facilitation of human IgG production in PBL-NOG-hIL-4-Tg mice.pptx

Presentation 1_Human interleukin-4-dependent facilitation of human IgG production in PBL-NOG-hIL-4-Tg mice.pptx

<p>Immune-humanized mouse models are indispensable tools for evaluating human immune responses and testing immune-based therapies; however, the induction of robust human antigen-specific immunoglobulin G (IgG) production remains limited due to species-specific incompatibilities. To investigate...

Full description

Saved in:
Bibliographic Details
Main Author: Yoshie Kametani (381802) (author)
Other Authors: Shino Ohshima (3229245) (author), Ryoji Ito (588817) (author), Yusuke Ohno (427990) (author), Soga Yamada (13824091) (author), Yuki Hoshino (485639) (author), Asuka Miyamoto (3229239) (author), Mao Suzuki-Ohno (22688504) (author), Nagi Katano (13824094) (author), Banri Tsuda (4112275) (author), Mariko Miyazawa (22688507) (author), Hirofumi Kashiwagi (13824082) (author), Daiki Kirigaya (16517130) (author), Tomoka Shimizu (13824088) (author), Mika Kojima (17081853) (author), Yusuke Kikuchi (4112278) (author), Shunsuke Nakada (22688510) (author), Rentaro Ohki (22688513) (author), Atsushi Yasuda (5681693) (author), Ayako Hirota (3564923) (author), Yukio Nakamura (39120) (author), Jerzy K. Kulski (3229236) (author), Tomotaka Mabuchi (17911345) (author), Hitoshi Ishimoto (13824097) (author), Takashi Shiina (18405) (author)
Published: 2025
Subjects:
Genetic Immunology
humanized mouse
humoral immunity
T cell receptor
antibody
repertoire
class switch
affinity maturation
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items