Searching for Synthetic Opioid Rescue Agents. 2: Identification of an Ultra-Potent Synthetic Opioid Rescue Agent

Searching for Synthetic Opioid Rescue Agents. 2: Identification of an Ultra-Potent Synthetic Opioid Rescue Agent

Ultrapotent synthetic opioids (UPSO) have become increasingly prevalent today, from being implicated in a mass casualty event to contaminating illicit drug supply across the country. These UPSOs are different than semisynthetic and naturally derived opioids, in the sense that UPSOs have a much great...

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Bibliographic Details
Main Author: Jocelyn Martin (18693398) (author)
Other Authors: Edem Onyameh (21527214) (author), Dan Luo (192943) (author), Joshua W. Powell (20980692) (author), Riya R. Trivedi (21527217) (author), Eric J. Woloshin (18693407) (author), Yating Zhang (218669) (author), Jakob D. Shaykin (18693404) (author), Emily D. Denehy (18693392) (author), Alexia R. Alsum (18693401) (author), Emily Prantzalos (11526775) (author), Qianru Jiang (18693416) (author), Tao Che (1372938) (author), Warren J. Alilain (16468158) (author), Jill R. Turner (3185361) (author), Michael T. Bardo (18693425) (author), Thomas E. Prisinzano (268174) (author)
Published: 2025
Subjects:
Biochemistry
Cell Biology
Neuroscience
Pharmacology
Biotechnology
Developmental Biology
Cancer
Mental Health
Chemical Sciences not elsewhere classified
wooden chest syndrome
much greater ability
mass casualty event
limited brain penetrance
lead toward developing
induced ventilatory depression
induced respiratory depression
increases minute ventilation
naturally derived opioids
fully reverses fentanyl
9 </ b
vitro </
ups opioids
new strategy
cause opioid
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