Comparison between simulation based estimates for boosts in GM HAI, IgG, and IgM that is experienced after an infection event as a function of acute GM HAI, IgG, and IgM titers individuals under the varying levels of observational noise.

Eitemau Tebyg

• Distribution of paired serological data that fall into probability buckets when using Model 9 (incorporating paired IgG, IgM, GM HAI, and acute GM HAI serological data) and the number of serological assays (RT-PCR, HAI, and EIA) that interpret the individual as having an infection.
  gan: Marco Hamins-Puértolas (15238661)
  Cyhoeddwyd: (2025)
• Acute and convalescent data for serological assays, colored by probability of infection found during model testing for Model 9. a) Geometric mean titers of a haemagglutination inhibition assay (GM HAI) for all four serotypes of dengue virus. b) Immunoglobulin G (IgG) c) Immunoglobulin M (IgM) d) Ratio of IgM to IgG at both acute and convalescent sera samples.
  gan: Marco Hamins-Puértolas (15238661)
  Cyhoeddwyd: (2025)
• Acute and convalescent samples from cohort study data for serological assays, colored by the number of serological assays (RT-PCR, HAI, and EIA) that interpret the individual as having an infection. a) Geometric mean titers of a haemagglutination inhibition assay (GM HAI) for all four serotypes of dengue virus. b) Immunoglobulin G (IgG) c) Immunoglobulin M (IgM) d) Ratio of IgM to IgG at both acute and convalescent serum samples.
  gan: Marco Hamins-Puértolas (15238661)
  Cyhoeddwyd: (2025)
• Relationship between estimated probability of a dengue virus infection (DENV) found during model testing for Model 9 (incorporating paired IgG, IgM, GM HAI, and acute GM HAI serological data) and the number of serological assays (RT-PCR, HAI, and EIA) that interpret the individual as having an infection.
  gan: Marco Hamins-Puértolas (15238661)
  Cyhoeddwyd: (2025)
• Simulated serological data using serosim and subsequent results using the full mixture model on (a) HAI, (b) IgG and (c) IgM data with additional observational noise.
  gan: Marco Hamins-Puértolas (15238661)
  Cyhoeddwyd: (2025)