HHA age-standardized death rates: WHO Africa vs. global and by subtype (2001–2021).

A, Comparison of WHO-African region to global age-standardised death rate due to HHA from 2000 to 2021. B, WHO Africa Region Age-standardised death rate by HHA subtype, 2000–2021. The global age-standardized death rate is represented as a line graph for...

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Main Author:	Temitope T Ojo (13268562) (author)
Other Authors:	Prince M Amegbor (18709930) (author), Farha Islam (19850826) (author), Joyce Gyamfi (3293661) (author), Andi Mai (22291001) (author), Carly M Malburg (22291004) (author), Deborah B Adenikinju (22291007) (author), Nicholas J Kassebaum (8383509) (author), Shimelis Tadesse Abebe (19184107) (author), Richard Gyan Aboagye (11062921) (author), Ganiyu Adeniyi Amusa (18346479) (author), Seth Christopher Yaw Appiah (8673417) (author), Haftu Asmerom Asmerom (19715341) (author), Isaac Sunday Chukwu (17255680) (author), Tadesse Asmamaw Dejenie (12197236) (author), Fitsum Wolde Demisse (18301738) (author), Gashaw Dessie (11512858) (author), Mengistie Diress (10136788) (author), Christopher Imokhuede Esezobor (18474798) (author), Habitu Birhan Eshetu (13267716) (author), Adeniyi Francis Fagbamigbe (4344979) (author), Sefineh Fenta (22291010) (author), Teferi Gebru Gebremeskel (8544399) (author), Segun Emmanuel Ibitoye (9154130) (author), Robel Hussen Kabthymer (10105700) (author), Woldeteklehaymanot Dagne Kassahun (19136566) (author), Biruk Getahun Kibret (19912263) (author), Osaretin Christabel Okonji (16415994) (author), Prof Mayowa O Owolabi (22291013) (author), Prof Léon Muepu M Tshilolo (22291016) (author), Berhanu Woldu (3555188) (author), Emmanuel K Peprah (9714998) (author)
Published:	2025
Subjects:	Medicine Biotechnology Immunology Cancer Science Policy Infectious Diseases Computational Biology Biological Sciences not elsewhere classified yet comprehensive assessments world health organization strengthened newborn screening sickle cell disorder health system interventions first systematic analysis diverse clinical complications despite overall declines death ensemble model codem ), supplemented 8 million individuals 09 &# 8211 04 &# 8211 adjusted life years standardized death rates reduce preventable deaths african region continues african region accounts xlink "> hemoglobinopathies specific estimates revealed estimated using dismod 2000 &# 8211 five years faced 2021 using data global hha prevalence disproportionate global burden african region specific rates years lived generated using multiplying prevalence global levels global burden disproportionate share 68 deaths estimated regional estimated 2 mortality estimates year intervals western sub urgent need ui 26 ui 2 thalassemias contributed sex -, saharan africa regression tool regional burden predominant contributor per 100
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HHA age-standardized death rates: WHO Africa vs. global and by subtype (2001–2021).

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