<b>Morin alleviates fructose-driven disturbance of podocyte mitochondrial energy metabolism by inhibiting AMPD activity to improve glomerular injury</b>
<p dir="ltr">High consumption of fructose is a significant risk factor for glomerular podocyte injury. We reported a novel mechanism that high fructose increased the activity of adenosine 5’-monophosphate deaminase (AMPD) in the purine nucleotide cycle (PNC), which contributed to mit...
में बचाया:
| मुख्य लेखक: | Luyi Huang (22583081) (author) |
|---|---|
| प्रकाशित: |
2025
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| विषय: | |
| टैग: |
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3D confocal imaging data of podocyte membranes from manually sectioned renal tissue from a Myosin 1e <sup>+/</sup><sup>Flox</sup> ROSA <sup>+/</sup><sup>mTmG</sup> Podocin-Cre <sup>+/</sup><sup>Tg</sup> transgenic mouse.
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3D live confocal image of live tissue previously passed through a sieve, from Myosin 1e <sup>+/</sup><sup>Flox</sup> ROSA <sup>+/</sup><sup>mTmG </sup>Podocin-Cre <sup>+/</sup><sup>Tg</sup> transgenic mouse
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Confocal section of a paraformaldehyde-fixed cryosection of kidney cortex from Myo1e <sup>+/Flox</sup><sup> </sup>ROSA <sup>+/mTmG</sup>Podocin-Cre <sup>+/Tg</sup> transgenic mouse stained with antibodies against ZO-1 and DAPI
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