Image 1_Moderate pyridoxal phosphate deficiency enhances neuronal excitability and promotes calcium dysregulation.jpeg
Objective<p>Pyridoxal 5′-phosphate (PLP), the active form of pyridoxine (vitamin B6), is essential for converting glutamate into the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Severe consequences of PLP deficiency due to genetic defects are well known, but the impact of modest...
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2025
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