Dually Decorated Palmitate-Containing Lipid Nanoparticles for the Targeted Delivery of siRNAs against HER2 and Hsp27 in HER2<sup>+</sup> Breast Cancer
Ionizable lipid nanoparticles (LNPs) have enabled significant advances in oligonucleotide (ON) therapeutics, resulting in the approval of the short interfering RNA (siRNA)-based formulation Onpattro. However, achieving cell-specific delivery remains challenging. We have developed palmitate-containin...
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2025
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