The analysis of the microbial structure based on linear discriminant analysis (A) and Random Forest (B), abundance analysis using EdgeR (C) according to the type of inflammatory disease and body weight in METAINFLAMMATION cohort.

<p>The most differentially abundant taxa between patients with low-grade MI and SLE according to BMI are represented in a bar graph LDA score, an estimation of the effect size. Only taxa meeting a <i>P</i> < 0.05 and LDA score significant threshold | > 2| are shown. Red, bact...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолч: Lourdes Chero-Sandoval (22683418) (author)
Бусад зохиолчид: Andrea Higuera-Gómez (22683421) (author), Begoña de Cuevillas (22683424) (author), Raquel Castejón (13980860) (author), María Martínez-Urbistondo (22683427) (author), Susana Mellor-Pita (22683430) (author), Víctor Moreno-Torres (9634628) (author), Daniel de Luis (22683433) (author), Amanda Cuevas-Sierra (9278315) (author), J. Alfredo Martínez (6989336) (author)
Хэвлэсэн: 2025
Нөхцлүүд:
Шошгууд: Шошго нэмэх
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
Тодорхойлолт
Тойм:<p>The most differentially abundant taxa between patients with low-grade MI and SLE according to BMI are represented in a bar graph LDA score, an estimation of the effect size. Only taxa meeting a <i>P</i> < 0.05 and LDA score significant threshold | > 2| are shown. Red, bacterial taxa statistically overrepresented in low-grade MI participants and high BMI; blue, bacterial taxa overrepresented in participants with low-grade MI and low BMI; green, bacterial taxa overrepresented in participants with SLE and high BMI and purple bacterial taxa overrepresented in participants with SLE and low BMI (A).The Random Forest analysis was performed with the importance plot showing the importance of each variable in the prediction of the model, where the first variable is the most important when discerning between a low and a high BMI (B). The differential abundance analysis performed using EdgeR between patients with low-grade MI and SLE are represented with a bar plot (<i>P</i> value corrected by FDR). Red boxes represent patients with SLE and low BMI; green boxes represent patients with SLE and high BMI; light blue boxes represent patients with low-grade MI and low BMI and purple boxes represent patients with low-grade MI and high BMI (C).</p>