Filamin A is regulated by miR-200c by repression of JUN as well as SRF-MRTF.

Filamin A is regulated by miR-200c by repression of JUN as well as SRF-MRTF.

<p>(a) After introduction of the TRIPZ-200c construct into MCF7 200c KO cells, miR-200c was re-expressed by 48 h of DOX induction and showed (b) significantly decreased FLNA expression. (c) <i>In silico</i> analysis of the FLNA promotor revealed 6 transcription factors which have a...

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Bibliographic Details
Main Author: Bojan Ljepoja (4921255) (author)
Other Authors: Christoph Schreiber (7901258) (author), Florian A. Gegenfurtner (6900935) (author), Jonathan García-Roman (7901261) (author), Bianca Köhler (7901264) (author), Stefan Zahler (288655) (author), Joachim O. Rädler (527784) (author), Ernst Wagner (60760) (author), Andreas Roidl (116002) (author)
Published: 2019
Subjects:
Biophysics
Cell Biology
Genetics
Molecular Biology
Physiology
Biotechnology
Developmental Biology
Cancer
Hematology
Infectious Diseases
Biological Sciences not elsewhere classified
breast cancer cells
MCF 7 cells
miR 200c
miR -200c expression
miR -200c
miR -200s induction
Inducible microRNA -200c decreases motility
transcription factors c-Jun
miR -200c inducible breast cancer cell lines
cell motility
ZEB
MRTF
miR -200c MDA-MB -231 cells
1 D microlane migration assays
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