Result of colocalization and functional enrichment analysis.

Result of colocalization and functional enrichment analysis.

<p><b>A.</b> This panel illustrates the colocalization results for DeP and RA. The left plot shows a scatter plot of -log10(p-values) for depression (x-axis) and RA (y-axis), with each point representing a SNP. The color of each point indicates the linkage disequilibrium (LD) with...

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Bibliographic Details
Main Author: Fu Sun (695282) (author)
Other Authors: Shirong Hui (21300056) (author), Bin Gong (175064) (author), Jinhua Gu (12700307) (author), Peng Huang (105814) (author)
Published: 2025
Subjects:
Genetics
Immunology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
significantly correlated regions
polygenic risk scores
higher prediction performance
future research aimed
critical communication network
wide association studies
local genetic correlations
div >< p
pleiotropic loci identification
local strategy
genetic interplay
using genome
ulcerative colitis
uc ),
summary statistics
side analyses
shared loci
sequential analysis
ra ),
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neuroimmune axis
main analyses
integrating genome
immune systems
genome wide
functional annotation
comprehensive analysis
cohort data
casual relationship
casual gene
autoimmune disorders
autoimmune diseases
also provides
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