Deregulation of genes and retrotransposons in blastocysts with mutations of Ogt at T931.

(A) Integrative Genomics Viewer (IGV) screenshot showing RNA-Seq reads around the T931 residue of Ogt for three representative genotypes of male blastocysts found in the dataset. Mutated nucleotides are colored in their containing reads or black barred...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Sara Formichetti (20536052) (author)
مؤلفون آخرون:	Agnieszka Sadowska (465534) (author), Michela Ascolani (20536055) (author), Julia Hansen (3907219) (author), Kerstin Ganter (20536058) (author), Christophe Lancrin (19341748) (author), Neil Humphreys (7308227) (author), Mathieu Boulard (49510) (author)
منشور في:	2025
الموضوعات:	Biophysics Biochemistry Genetics Developmental Biology Hematology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified murine allelic series genetic gradual reduction reducing ogt ’ perturbed ogt ’ div >< p ogt activity unveils ogt ’ ogt </ ogt ). mild reduction enzymatic activity catalytic activity vivo </ single enzyme reversible glycosylation proliferating cells mutant embryos identified hypomorphic endogenous retroviruses embryonic lethality embryonic development early development cytoplasmic proteins
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Deregulation of genes and retrotransposons in blastocysts with mutations of <i>Ogt</i> at T931.

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