Photoactivatable Electrophilic Glycosylselenosulfonates for Ultrafast Modification of Alkynes and Thiols

Glycosylseleno scaffolds exhibit wide-ranging applications in multidisciplinary fields, particularly in drug discovery and biophysical chemistry, where they serve as valuable tools for biomolecular structural analysis. However, efficient methods toward glycosylseleno scaffolds remain underexplored....

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Bibliografiske detaljer
Hovedforfatter:	Weitao Yan (4476130) (author)
Andre forfattere:	Wenchao Liu (330964) (author), Qinshuo Zhang (21481755) (author), Wentao Lin (8795450) (author), Yujie Liao (11413328) (author), Yiqun Geng (1633150) (author), Ruo Wang (2994693) (author), Chunfa Xu (1528972) (author)
Udgivet:	2025
Fag:	Biophysics Biochemistry Medicine Pharmacology Biotechnology Infectious Diseases Space Science Chemical Sciences not elsewhere classified Information Systems not elsewhere classified mild reaction conditions findings collectively underscore exceptionally fast rate biomolecular structural analysis aqueous conditions highlights advances synthetic methodologies photoactivatable electrophilic glycosylselenosulfonates efficient labeling techniques glycosylseleno sulfonates complex biological systems protein labeling electrophilic properties glycosylseleno scaffolds glycosylseleno moieties valuable tools upon photoirradiation ultrafast modification thereby facilitating successful peptide straightforward incorporation stable reagents ranging applications radical addition operational simplicity novel class negligible interference multidisciplinary fields method ’ functional studies drug discovery developing rapid containing molecules chemical research broad applicability biophysical chemistry bioorthogonal applications achieving completion 1 min
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Photoactivatable Electrophilic Glycosylselenosulfonates for Ultrafast Modification of Alkynes and Thiols

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