Analysis of NGS results for IL-6 aptamer selection.

<p>A) Scatterplot showing the relationship between Z-score and fold change in the top 10,000 sequences from the IL-6/Naïve selection. B) Density plot comparing the frequency of the top 10,000 IL-6/Naïve selection sequences in IL-6/HSA and IL-6/Ultralink selections. C) Density plot comparing th...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Cathal Meehan (14129680) (author)
مؤلفون آخرون:	Erika L. Hamilton (20715499) (author), Chloé G. Mansour (20715502) (author), Soizic Lecocq (4739196) (author), Cole J. Drake (20715505) (author), Yisi An (20715508) (author), Emily Rodrigues (8416182) (author), Gregory Penner (2408914) (author)
منشور في:	2025
الموضوعات:	Microbiology Molecular Biology Biotechnology Evolutionary Biology Immunology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified 29 × 10 selex method since neomers )</ p div >< p replicating immune tolerance driving aptamer specificity possible library sequences immune tolerance neomer library drive specificity new method method represents immune system aptamer selection aptamer identification vitro evolution structural diversity silico approach significant constraints significant constraint secondary structure remove antibodies random nucleotides powerful means novel platform high level fixed sequences counter selection commercial efficacy
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Analysis of NGS results for IL-6 aptamer selection.

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