Optimizing Neuronal Calcium Flux Analysis: A Python Framework for Alzheimer's and TBI Studies

Optimizing Neuronal Calcium Flux Analysis: A Python Framework for Alzheimer's and TBI Studies

<p dir="ltr">This study presents a Python-based framework for analyzing calcium flux in cortical neurons, particularly in the context of Alzheimer’s disease and traumatic brain injury (TBI). Cortical neurons, central to memory and cognition, are highly susceptible to calcium dysregul...

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Main Author: Huiying Huang (490768) (author)
Other Authors: Krishna Vijay (22327248) (author), Nicole Ching (22327381) (author), Srirohan Pokuru (22327384) (author), Max Arola (22327385) (author), Maya Krishnan (22327386) (author), Yolotzin Mendez (22327389) (author), Connor Lee (22327243) (author), Crystal Cheng (22327391) (author), Chengbiao Wu (12863681) (author), Linda Z. Shi (19183704) (author), Veronica Gomez-Godinez (9307754) (author)
Published: 2025
Subjects:
Neurology and neuromuscular diseases
Cortical neurons
Calcium flux
Alzheimer’s disease
Traumatic brain injury (TBI)
Laser-Induced Shockwave
Python automation
Cellpose segmentation
Exponential decay modeling
Image-based cell analysis
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