<i>PIK3R1</i> and <i>G0S2</i> are human placenta-specific imprinted genes associated with germline-inherited maternal DNA methylation

<i>PIK3R1</i> and <i>G0S2</i> are human placenta-specific imprinted genes associated with germline-inherited maternal DNA methylation

<p>Genomic imprinting is the parent-of-origin specific monoallelic expression of genes that result from complex epigenetic interactions. It is often achieved by monoallelic 5-methylcytosine, resulting in the formation of differentially methylated regions (DMRs). These show a bias towards oocyt...

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Main Author: Dagne Daskeviciute (21606709) (author)
Other Authors: Becky Sainty (21606712) (author), Louise Chappell-Maor (2559871) (author), Caitlin Bone (21606715) (author), Sarah Russell (378518) (author), Isabel Iglesias-Platas (157423) (author), Philippe Arnaud (28668) (author), Ana Monteagudo-Sánchez (3343796) (author), Maxim V.C Greenberg (21606718) (author), Keran Chen (1699822) (author), Africa Manero Azua (21635300) (author), Guiomar Perez de Nanclares (8448942) (author), Jon Lartey (320918) (author), David Monk (24463) (author)
Published: 2025
Subjects:
Cell Biology
Genetics
Molecular Biology
Developmental Biology
Cancer
Infectious Diseases
Mathematical Sciences not elsewhere classified
Genomic imprinting
placenta
differentially methylated regions
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