Comparison of ecDNA and DNase in GCTs patients according to stage (A, B) and number of metastatic sites (C, D).

Comparison of ecDNA and DNase in GCTs patients according to stage (A, B) and number of metastatic sites (C, D).

<p>Comparison of ecDNA and DNase in GCTs patients according to stage (A, B) and number of metastatic sites (C, D).</p>

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Mego Michal (22783828) (author)
مؤلفون آخرون: Vlkova Barbora (22783831) (author), Kalavska Katarina (22783834) (author), Pastorek Michal (22783837) (author), Cierna Zuzana (22783840) (author), Sestakova Zuzana (22783843) (author), Chovanec Miroslav (22783846) (author), Udvorkova Natalia (22783849) (author), Kucerova Lucia (22783852) (author), Celec Peter (22783855) (author)
منشور في: 2025
الموضوعات:
Biochemistry
Cell Biology
Molecular Biology
Biotechnology
Immunology
Developmental Biology
Cancer
Science Policy
Infectious Diseases
translational utility remains
significantly worse progression
neutrophil extracellular trap
immune inflammatory index
five times higher
different subcellular origin
2 cisr xenografts
prolonged animal survival
human recombinant dnase
worse overall survival
total extracellular dna
worse clinical outcome
endogenous dnase levels
higher total ecdna
117 gct patients
gct patients compared
plasma dnase level
overall survival
clinical outcome
total ecdna
os compared
free survival
ecdna levels
gct patients
therapeutic outcome
plasma dnase
exogeneous dnase
dna species
dna damage
gct model
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unfavourable response
pulmozyme combination
prognostic value
plasma ecdna
lower ecdna
low level
inverse correlation
inferior pfs
high level
ecdna ),
delayed growth
data demonstrate
data confirm
combined treatment
05 ).
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