SAS-1 loss leads to impaired centriole integrity during oogenesis.

<p><b>A.</b> Schematic of the gonad of a young adult hermaphrodite showing successive stages of gametogenesis, with early mitotic region, followed by early meiotic prophase, before loop region and cellularization. Mature oocytes traverse the spermatheca where fertilization takes pl...

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Bibliographic Details
Main Author:	Keshav Jha (13805097) (author)
Other Authors:	Alexander Woglar (204503) (author), Coralie Busso (3610127) (author), Georgios N. Hatzopoulos (16763834) (author), Tatiana Favez (22478147) (author), Pierre Gönczy (434319) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Cell Biology Genetics Neuroscience Physiology Immunology Developmental Biology Cancer Mental Health Computational Biology Physical Sciences not elsewhere classified partially redundant manner molecular epistasis experiments findings help clarify based organelles critical 1 localizes next div >< p binding protein sas ensures centriole integrity 1 recruits ssna centriole integrity organelle integrity centriole assembly centriole architecture 1 localization transition zone sjögren ’ sensory neurons null alleles null allele incompletely understood elegans </ early embryo
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SAS-1 loss leads to impaired centriole integrity during oogenesis.

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