Learning of a visual discrimination task and optogenetic manipulations in head-fixed mice.

Learning of a visual discrimination task and optogenetic manipulations in head-fixed mice.

<p><b>A)</b> Schematic of setup. Mice are head-fixed on a cylindrical Styrofoam treadmill and static gratings are presented on a monitor to the right eye (contralateral to photostimulated side). A spout located in front of the mouse delivers milk during rewarded trials. <b>B)...

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Detalles Bibliográficos
Autor Principal: Lilia Kukovska (22683586) (author)
Outros autores: Katharina A. Wilmes (22683589) (author), Natsumi Y. Homma (22683592) (author), Claudia Clopath (324706) (author), Jasper Poort (22683595) (author)
Publicado: 2025
Subjects:
Biochemistry
Neuroscience
Developmental Biology
Science Policy
Mental Health
Biological Sciences not elsewhere classified
xlink "> inhibition
three major factors
strong competitive interactions
photon imaging showed
balanced cortical activity
primary visual cortex
sustained v1 activity
combined optogenetic activation
v1 cells captured
moderate pv activation
moderate activation
visual discriminations
expressing cells
nonlinear activation
dependent activation
activation strength
task difficulty
stimulus onset
perceptual discrimination
difficult discriminations
delineates conditions
circuit model
behavioral effects
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