PIP2 activation of the cardiac IKs potassium channel
<p dir="ltr">The IKs channel complex, composed of the voltage-gated potassium channel KCNQ1 and its regulatory subunit KCNE1, is essential for the termination of cardiac action potentials. The function of KCNQ1 and IKs requires PIP2, and its depletion abolishes channel opening. Previ...
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2025
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