Gag vaccine designed: a) Proposed Gag-HIV vaccine construct; b) Best 3D model of designed Gag vaccine; c) Confirmation of vaccine structure defined by crystallography using the ERRAT tool; d) Ramachandran plot of the refined Gag vaccine was created with the PDBsum software; e) Protein structure analysis of vaccine designed by Prosa-web tool.

<p>Gag vaccine designed: a) Proposed Gag-HIV vaccine construct; b) Best 3D model of designed Gag vaccine; c) Confirmation of vaccine structure defined by crystallography using the ERRAT tool; d) Ramachandran plot of the refined Gag vaccine was created with the PDBsum software; e) Protein struc...

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Bibliographic Details
Main Author:	Ava Hashempour (11753878) (author)
Other Authors:	Nastaran Khodadad (17535416) (author), Peyman Bemani (10651254) (author), Younes Ghasemi (3125685) (author), Shokufeh Akbarinia (17535419) (author), Reza Bordbari (19751532) (author), Amir Hossein Tabatabaei (19751535) (author), Shahab Falahi (18301765) (author)
Published:	2024
Subjects:	Medicine Microbiology Molecular Biology Biotechnology Immunology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified molecular dynamic stimulation immunological simulation showed div >< p codon optimization ensured simulate immune responses strong binding affinities human vaccine model 1 gag </ strong binding gag </ 1 </ consistent responses human cells e </ coli </ γ induction yet achieved world ’ vaccine models vaccine formulated successful translation significant progress reverse vaccinology experimental verification epitopes located designed constructs conserved domains challenges faced bcl epitopes approximately 93 100 major
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