Molecular dynamic simulation of the HP_VaX_V1-TLR7 and HP_VaX_V2-TLR8 constructs.

<p>(a) Deformability of the protein structures, illustrating the flexibility at each residue. (b) B-factor (or temperature factor) analysis, showing the degree of atomic displacement. (c) Eigenvalues from the Normal Mode Analysis (NMA), indicating the stiffness of the modes. (d) Variance map,...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Md. Nahian (20571297) (author)
مؤلفون آخرون:	Md. Rasel Khan (20571300) (author), Fabiha Rahman (20691385) (author), Hossain Mohammed Reza (20691388) (author), Imren Bayil (18887023) (author), Tanjum Ahmed Nodee (20691391) (author), Tabassum Basher (20691394) (author), Mostafizur Rahaman Sany (20691397) (author), Rabeya Najnin Munmun (20691400) (author), S. M. Ariful Habib (20691403) (author), Lincon Mazumder (15455463) (author), Mrityunjoy Acharjee (3761959) (author)
منشور في:	2025
الموضوعات:	Microbiology Biotechnology Immunology Cancer Infectious Diseases Space Science Biological Sciences not elsewhere classified Information Systems not elsewhere classified secondary mrna structure optimized restriction sites current drug treatments control infections caused computational approaches offer epitope subunit vaccine chosen vaccine constructs licensed vaccines available epitope subunit vaccines proposed vaccine candidates helicobacter pylori </ molecular docking simulations vaccine candidates molecular docking pylori </ safe vaccines immune simulations silico </ h </ − 20 viable strategy viable alternative vaca ). structural flexibility strongly immunogenic scale production potent b population coverage persistently infects performed using peptic ulcers negative bacterium mediated immunity laboratory validation increased risk immunoinformatic strategy human stomach gastric cancer favored regions extremophilic characteristics evaluated based designing antigenic codon adaptation bacterium make analyses suggest
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Molecular dynamic simulation of the HP_VaX_V1-TLR7 and HP_VaX_V2-TLR8 constructs.

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