Image 2_CRISPR/Cas9-based discovery of ccRCC therapeutic opportunities through molecular mechanism and immune microenvironment analysis.tif

Image 2_CRISPR/Cas9-based discovery of ccRCC therapeutic opportunities through molecular mechanism and immune microenvironment analysis.tif

Introduction<p>Clear cell renal cell carcinoma is a common and aggressive form of renal cell carcinoma. Its incidence continues to rise, and metastatic recurrence leads to poor clinical outcomes. Current prognostic biomarkers lack reliability. We integrated multi-omics data to discover key ccR...

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Bibliographic Details
Main Author: Bo Han (84102) (author)
Other Authors: Weiyang Liu (4975958) (author), Wanhui Wang (3812164) (author), Zhuolun Li (10450225) (author), Bosen You (6741617) (author), Dongze Liu (12993036) (author), Yunfeng Nan (21692651) (author), Tiankai Ding (21692654) (author), Zhou Dai (1646161) (author), Yantong Zhang (21692657) (author), Wei Zhang (405) (author), Qing Liu (20889) (author), Xuedong Li (435153) (author)
Published: 2025
Subjects:
Genetic Immunology
CRISPR-Cas9 screening
ccRCC
prognostic model
MELK
immunotherapy
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