Differential genome-wide JUND binding reveals increased JUND binding in the term not in labor myometrium compared to the laboring myometrium.

A) Venn diagram depicting overlapping JUND peaks obtained from ChIP-seq conducted from myometrium tissue samples at term not in labor (TNIL) and term labor (TL). B) Volcano plot shows differentially enriched regions [abs log2 fold change ≥ 1, p-valu...

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Bibliographic Details
Main Author:	Nawrah Khader (9128150) (author)
Other Authors:	Anna Dorogin (9128153) (author), Oksana Shynlova (6085517) (author), Jennifer A. Mitchell (9128156) (author)
Published:	2025
Subjects:	Microbiology Cell Biology Genetics Molecular Biology Immunology Developmental Biology Infectious Diseases Computational Biology Biological Sciences not elsewhere classified varying myometrial states undergoes crucial transitions study examines changes seq data identifies primary transcript levels molecular mechanisms governing generating coordinated contractions findings open avenues laboring myometrial tissues including genes involved associated gene expression select myometrial contraction intergenic jund peaks preventing premature labor associated genes premature labor tl tissues xlink "> upregulated transcripts transcriptional regulation total rna shedding light serious complications sequencing reveals research enhances regulatory switch progesterone receptor potentially leading muscular layer labor onset jund plays improved interventions enhancer rnas driving processes contractile switch
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Differential genome-wide JUND binding reveals increased JUND binding in the term not in labor myometrium compared to the laboring myometrium.

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