Mosaic S-6P heterotrimer construct sequences, purification process, and characterizations.

<p><b>(A)</b> Color-coded S-6P domains on the cartoon diagram with annotated domain organization (PDB: 6VSB). S1: receptor-binding subunit; S2: fusion subunit; NTD: N-terminal domain; RBD: receptor-binding domain; FP: fusion peptide; HR1: heptad repeat 1; CH: central helix; CD: con...

Cur síos iomlán

Sábháilte in:

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Chengbo Chen (11046348) (author)
Rannpháirtithe:	Klaus N. Lovendahl (22290965) (author), Julie M. Overbaugh (22290968) (author), Kelly K. Lee (9740516) (author)
Foilsithe / Cruthaithe:	2025
Ábhair:	Biophysics Molecular Biology Immunology Infectious Diseases Virology Biological Sciences not elsewhere classified maintained without misfolding glycosylation profiles likewise exchange mass spectrometry evade immune responses bivalent mrna vaccines provide important information antigenically important regions xlink "> sars binding subunit compared specific dynamics similar polyvalent immunogen co enhanced immunogen display determined whether co mosaic spike trimers mosaic spike dynamics 2 variants results mosaic heterotrimer antigens assembly </ p spike antigens mosaic trimers important considerations mosaic heterotrimers understanding whether different sars multiple variants emerging variants 2 variants stabilizing effect retained protomer receptor binding preserved relative interprotomer crosstalk infection throughout homotrimer counterparts genetically close g614 heterotrimer epitope presentation
Clibeanna:	Cuir clib leis Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!

Mosaic S-6P heterotrimer construct sequences, purification process, and characterizations.

Míreanna comhchosúla