Acoustic-Magnetic Responsive Nanomotor Augments Oral Drug Delivery by Gastrointestinal Site Navigation and Mucus Layer Penetration

Oral administration is a traditional, safe, and widely used drug delivery strategy. However, the delivery efficiency of the oral drug delivery system is hindered by the long gastrointestinal tract, filled with dense and viscous mucus. Herein, we presented an acoustic-magnetic responsive nanomotor (M...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Zhi-Hao Wang (151090) (author)
مؤلفون آخرون:	Xuejiao Zeng (5264519) (author), Shuhao Zhang (3804106) (author), Hailong Li (216327) (author), Jianchao Zhou (6709394) (author), Yefei Yang (21212038) (author), Wanting Huang (3814585) (author), Fengqin Zhao (4992020) (author), Zhongyang Liu (1863094) (author), Junjie Liu (193511) (author), Yurong Hu (5126702) (author), Jinjin Shi (815355) (author)
منشور في:	2025
الموضوعات:	Biophysics Medicine Pharmacology Biotechnology Space Science Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified Physical Sciences not elsewhere classified various intestinal segments small intestinal navigation shaped structure composed orthotopic colorectal cancer effective hypoglycemic time broad application prospects long gastrointestinal tract gastrointestinal site navigation orally administered drugs magnetic responsive nanomotor mucus layer penetration ultrasound propulsion increased oral relative bioavailability mucus penetration efficiency mucus penetration nanomotor increased gastrointestinal diseases viscous mucus ultrasound radiation loaded drugs versatile nanomotor delivery efficiency anchoring efficiency universal strategy mesoporous silica iron tetroxide different diseases diabetes rats clinical conversion
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Acoustic-Magnetic Responsive Nanomotor Augments Oral Drug Delivery by Gastrointestinal Site Navigation and Mucus Layer Penetration

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