Time-restricted eating in Huntington’s disease study design.

<p>We propose a prospective interventional, open-label, single-arm trial with a target enrollment of 25 participants. Baseline testing will take place approximately one week prior to the TRE onset. The lead-in period will consist of seven days of lifestyle tracking which will be followed by 12...

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Bibliographic Details
Main Author:	Russell G. Wells (20933789) (author)
Other Authors:	Lee E. Neilson (20933792) (author), Andrew W. McHill (13017186) (author), Amie L. Hiller (5793722) (author)
Published:	2025
Subjects:	Medicine Neuroscience Physiology Mental Health Virology recent research indicates lower oxidative stress including lifestyle changes despite significant efforts standard hd behavioral scale clinical trials hd remain elusive hd animal models additional exploratory measures evaluate sleep quality evaluate participant adherence specific time window improve cognitive performance enhance mitochondrial function div >< p slow disease progression early manifest hd mitochondrial function secondary measures hd populations disease progression vital signs versus post stimulate autophagy shown potential serum biomarkers restricted eating psychiatric disturbances prospective interventional physical activity late prodromal intervention assessment intermittent fasting include pre huntington ’ future large efficacious treatments dietary composition cognitive impairment clinical efficacy caloric intake 25 participants
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Time-restricted eating in Huntington’s disease study design.

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