Adversely interacting drug pairs and non-interacting drug pairs significantly differ with regard to the 11 features selected.

Adversely interacting drug pairs and non-interacting drug pairs significantly differ with regard to the 11 features selected.

<p>(a) Schematics of calculating indication similarity and side effect similarity features. (b) Indication similarity score of hierarchy level PT, HLGT and SOC between two drugs. (c) Side effect similarity score of hierarchy level HLT and HLGT between two drugs. (d) Schematics of calculating t...

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Bibliographic Details
Main Author: Sheng Qian (5944997) (author)
Other Authors: Siqi Liang (3664828) (author), Haiyuan Yu (23735) (author)
Published: 2019
Subjects:
Biochemistry
Genetics
Neuroscience
Pharmacology
Biotechnology
Mental Health
Infectious Diseases
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
gradient boosting-based classifier
drug-drug interaction prediction
non-interacting drug pairs
DDI
novel training scheme
drug pairs
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