Sensitivity vs Competing Proton Transfer Reactions: Addressing Key Parameters of Ion Chemistry in Ion Mobility Spectrometry

Sensitivity vs Competing Proton Transfer Reactions: Addressing Key Parameters of Ion Chemistry in Ion Mobility Spectrometry

Ion mobility spectrometers (IMS) are widely used in various gas sensing applications due to their high sensitivity and rapid analysis times. However, in complex gas mixtures, reactions between the protonated target analyte and interfering species can lead to discrimination of analytes with low gas b...

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Bibliographic Details
Main Author: Christoph Schaefer (9357141) (author)
Other Authors: Stefan Zimmermann (1694173) (author)
Published: 2025
Subjects:
Biophysics
Biochemistry
Infectious Diseases
Space Science
Chemical Sciences not elsewhere classified
rapid analysis times
protonated target analyte
complex gas mixtures
complex chemical backgrounds
addressing key parameters
low gas basicity
key operating parameters
ion suppression caused
thereby enhancing sensitivity
minimize competing reactions
detecting target analytes
decreasing operating pressure
operating pressure
low pressure
ion chemistry
reducing sensitivity
increase sensitivity
high sensitivity
widely used
results demonstrate
reaction time
promising strategies
operating ims
kinetic model
interfering species
instrumental design
high concentrations
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