Figure 2 from Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma

Figure 2 from Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma

<p>CDS PDX models recapitulated the phenotypic characteristics and transcriptional profiles of the primary tumor. <b>A,</b> Histologic and IHC features of CDS patient samples and corresponding PDXs at different <i>in vivo</i> passages (P1, first passage; P3, third passa...

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主要作者: Marianna Carrabotta (8193039) (author)
其他作者: Maria Antonella Laginestra (9162509) (author), Giorgio Durante (14954974) (author), Caterina Mancarella (504222) (author), Lorena Landuzzi (278853) (author), Alessandro Parra (8713428) (author), Francesca Ruzzi (13950602) (author), Lisa Toracchio (14954977) (author), Alessandra De Feo (380645) (author), Veronica Giusti (14954980) (author), Michela Pasello (8193048) (author), Alberto Righi (10025103) (author), Pier-Luigi Lollini (14954983) (author), Emanuela Palmerini (14954986) (author), Davide Maria Donati (9944270) (author), Maria Cristina Manara (9081374) (author), Katia Scotlandi (14954989) (author)
出版: 2025
主题:
Cancer
Cancer Biology
Molecular and Cellular Biology
Therapeutic Research and Development
Methods and Technology
Cell Signaling
Oncogenes & Tumor Suppressors
Preclinical Models
Xenograft models
Sarcomas
Translational Research
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