Marine-Derived Bisindole Alkaloid (R)-6'-Debromohamacanthin B as a Dual-Acting Anti-Pathogenic Agent that Targets <i>Pseudomonas aeruginosa</i> Virulence, Biofilm Formation, and Host Immune Responses

Marine-Derived Bisindole Alkaloid (R)-6'-Debromohamacanthin B as a Dual-Acting Anti-Pathogenic Agent that Targets <i>Pseudomonas aeruginosa</i> Virulence, Biofilm Formation, and Host Immune Responses

<p dir="ltr"><i>P. aeruginosa</i> is a refractory pathogen with strong quorum sensing (QS)-regulated virulence, biofilm formation, and the ability to induce harmful inflammation in the host. To develop a strategy that minimizes the risk of resistance development, we ident...

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Huvudupphovsman: Huiyan Li (22529084) (author)
Övriga upphovsmän: Dan-Dan Li (22529091) (author), Huayue Li (22529130) (author), Wen-Xin Niu (22529131) (author), Joon-Hee Lee (22529133) (author)
Publicerad: 2025
Ämnen:
Bacteriology
pseudomonas aeruginosa
anti-pathogenic therapy
Quorum sensing inhibition
anti-biofilm
host immune modulation
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