IL-1β release, with and without a caspase 8 inhibitor, and caspase-8 cleavage in BMDM exposed to CoCrMo particles or Co2+.

Bone marrow-derived macrophages (BMDM) from wild-type mice were primed with 500 ng/mL of lipopolysaccharide for 3 h, then exposed to 3.4-μm spherical CoCrMo particles or Co2+ for 18 h in the presence or absence of a caspase-8 inhibitor (Z-IETD-FMK). Interleukin-1β (IL...

全面介绍

Saved in:

书目详细资料
主要作者:	Nasteho Abdoulkader (22641176) (author)
其他作者:	Jennifer Archibald (22641179) (author), Morgane Lignereux (22641182) (author), Eric A. Lehoux (2947641) (author), Isabelle Catelas (4909363) (author)
出版:	2025
主题:	Cell Biology Genetics Molecular Biology Neuroscience Biotechnology Immunology Developmental Biology Marine Biology Cancer Science Policy Infectious Diseases Virology reactive oxygen species process putatively linked 4 &# 956 >< sup >< 2 +</ sup ></ sup >), metal ions released div >< p 1 &# 946 3 +</ sup inflammatory response triggered determine whether il identifying mechanisms involved cathepsin b dependent 1β release induced nlrp3 inflammasome activation metal ions cathepsin b whereas activation inflammatory response >), nlrp3 whether nlrp3 nlrp3 inflammasome nlpr3 inflammasome wt </ whether caspase type (< therefore critical targeting nlrp3 occurred independently nlrp3 </ macrophage pro lysosomal destabilization induce il includes interleukin implant failure findings highlight dependent release deficient (< corrosion products casp1 </ bone marrow analysis suggested 1β release
标签:	添加标签没有标签, 成为第一个标记此记录!

IL-1β release, with and without a caspase 8 inhibitor, and caspase-8 cleavage in BMDM exposed to CoCrMo particles or Co<sup>2</sup><sup>+</sup>.

相似书籍