Model comparisons for simulated data with differing amounts of observational noise.

Eitemau Tebyg

• Relative observational noise by assay and dataset.
  gan: Marco Hamins-Puértolas (15238661)
  Cyhoeddwyd: (2025)
• Simulated serological data using serosim and subsequent results using the full mixture model on (a) HAI, (b) IgG and (c) IgM data with additional observational noise.
  gan: Marco Hamins-Puértolas (15238661)
  Cyhoeddwyd: (2025)
• Comparison between simulation based estimates for boosts in GM HAI, IgG, and IgM that is experienced after an infection event as a function of acute GM HAI, IgG, and IgM titers individuals under the varying levels of observational noise.
  gan: Marco Hamins-Puértolas (15238661)
  Cyhoeddwyd: (2025)
• Comparison of each accuracy metric (sensitivity, specificity, F1, and area under the curve for reporter operator curve (AUC ROC)) on each model. Models are defined by which assays were incorporated (i.e., HAI, IgG, and/or IgM). Bolded values represent the best performing model for the infection definition and metric of interest.
  gan: Marco Hamins-Puértolas (15238661)
  Cyhoeddwyd: (2025)
• Characteristics for Kamphaeng Phet cohort studies split by source (KPS1 and KFCS) as well as across the entire dataset. Information on age, hospitalization as well as serological assay results for RT-PCR, haemagglutination inhibition assay (HAI), and enzyme immunoassay (EIA) are presented.
  gan: Marco Hamins-Puértolas (15238661)
  Cyhoeddwyd: (2025)