Increased nuclear tubulin abundance inhibits spindle extension.

<p>A) Time-lapse confocal imaging of 3D7 +GlcN Slp +/-GlcN parasites undergoing schizogony stained with SPY555-Tubulin (magenta). Maximum intensity projections are shown. Scale bars, 1.5 μm. B) Quantification of first (3D7+GlcN (n = 20), Slp-GlcN (n = 18), Slp+GlcN (n = 31)) and second (3D7+Gl...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Christoph Wenz (15389318) (author)
مؤلفون آخرون:	Caroline Sophie Simon (15389321) (author), Tatiany Patricia Romão (15389324) (author), Vanessa Saskia Stürmer (15389327) (author), Marta Machado (1434952) (author), Natacha Klages (9502817) (author), Anja Klemmer (15389330) (author), Yannik Voß (14709658) (author), Markus Ganter (14709661) (author), Mathieu Brochet (149272) (author), Julien Guizetti (11530207) (author)
منشور في:	2023
الموضوعات:	Biophysics Biochemistry Microbiology Cell Biology Genetics Molecular Biology Pharmacology Hematology Biological Sciences not elsewhere classified Physical Sciences not elsewhere classified study thereby identifies regulating tubulin levels plasmodium falciparum </ lapse microscopy revealed centrosomal proteins conserved aberrant mitotic spindles intranuclear tubulin abundance daughter cell formation centriolar plaque might centriolar plaque consists free intranuclear compartment div >< p centriolar plaque intranuclear compartment daughter cells extranuclear compartment significantly interfere significantly increased reduced number nuclear pore novel centrin multiple rounds like structure like protein like centrin human blood growth delay functional link extranuclear part dna replication connected via conditional knock blood stages
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Increased nuclear tubulin abundance inhibits spindle extension.

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