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Results of CFU counts after 8 weeks of culture on the two lungs homogenates. All values are represented by a dot, black horizontal bar is the mean for the group A. Dot plot representing results of M1 for treated B. Dot plot representing results of M2 fo...

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Bibliographic Details
Main Author:	Antoine Froment (19762213) (author)
Other Authors:	Julia Delomez (19762216) (author), Sophie Da Nascimento (8220786) (author), Alexandra Dassonville-Klimpt (19343707) (author), Claire Andréjak (11721492) (author), François Peltier (19762219) (author), Cédric Joseph (19762222) (author), Pascal Sonnet (2570548) (author), Jean-Philippe Lanoix (1604716) (author)
Published:	2024
Subjects:	Biochemistry Biotechnology Immunology Cancer Infectious Diseases Virology Computational Biology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified new active molecules 83 ± 0 82 ± 0 70 ± 0 43 ± 0 often poorly tolerated lowest cfu count emb -(-)- emq emb -(+)- emq div >< p clarithromycin resistant strains 26 ), rif 18 ), mfq mefloquine ((+)- emq mycobacterium avium </ enantiomers ((+) erythro group 3 months gold standard treatment evaluate drug efficacy 15 ), clr 3 months (+)- emq better tolerated avium </ (-)- erythro emb group vivo </ vitro </ untreated group treatment groups time point still long significant difference shown efficacy prevent selection murine model mouse model lung homogenates enantiomers appear c mice besides emergence aerosol model 5 mice 25 ). 21 ). 005 ).
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