IMP1/ZBP1 inhibition affects transcripts involved in motility and cytoskeleton regulation.

IMP1/ZBP1 inhibition affects transcripts involved in motility and cytoskeleton regulation.

<p><b>(A)</b> Schematic representation of a transwell with 1-µm-diameter pore used for the isolation of PeMPs <b>(A</b><sup><b>i</b></sup><b>)</b>. Cell material from the upper compartment was removed with a cotton swab and total RNA...

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المؤلف الرئيسي:	Josune Imaz-Iruretagoyena (22593465) (author)
مؤلفون آخرون:	Maite Blanco-Urrejola (8925752) (author), Irene Núñez-García (22593468) (author), Irene García-Toledo (22593471) (author), Luis C. Fernández-Beltrán (12291779) (author), Mar Márquez (22593474) (author), Silvia Corrochano (618848) (author), Amanda Sierra (3168117) (author), Jimena Baleriola (53412) (author)
منشور في:	2025
الموضوعات:	Biophysics Cell Biology Genetics Molecular Biology Neuroscience Immunology Cancer Biological Sciences not elsewhere classified Physical Sciences not elsewhere classified lamellar directed migration binding protein imp1 fundamental microglial functions local protein synthesis increasing evidence suggests div >< p peripheral microglial processes localized translation occur microglial inflammatory response inflammation </ p microglial processes localized translation local translation scant evidence actb </ zbp1 impaired work contributes target compartments subcellular proteomes regulate motility recent findings polarized cells pemp motility mrna polarizes mrna polarization mrna localization molecular mechanism mechanistic insight locally translated latter mechanism glial projections glial cells functional significance filopodia distribution cell soma best studied bacterial lipopolysaccharides asymmetric distribution assembled either also required
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