Substrate recognition diversity and transport dynamics of ABCC1

Substrate recognition diversity and transport dynamics of ABCC1

The atomic coordinates and cryo-EM density maps have been deposited in the Protein Data Bank (PDB) and Electron Microscopy Data Bank (EMDB) under accession codes PDB: 9LGC and EMDB: EMD-63061 for GSH-vincristine-bound ABCC1, PDB: 9LG8 and EMDB: EMD-63057 for GSH-E1SO4-bound ABCC1, PDB: 9LGA and EMDB...

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Dettagli Bibliografici
Autore principale: Pu Gao (14074898) (author)
Altri autori: Panpan Sun (20780651) (author), Kexin Liu (20780639) (author), Linnan Zhang (22054337) (author), Qixiang Zhang (20560143) (author), Yina Gao (20780657) (author), Zhaolong Li (20780654) (author), Yalan Zhu (19435991) (author), Songqing Liu (20780660) (author), Liguo Zhang (20780666) (author), Ang Gao (20780663) (author)
Pubblicazione: 2025
Soggetti:
Molecular Biology
ABCC1; MRP1; ABC Transporter; Multidrug resistance; leukotriene C4; estrogen sulfate; glutathione; cGAMP; verapamil; Vincristine
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