Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>

Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>

To investigate the material basis and mechanisms underlying the therapeutic effects of <i>Aglaia perviridis</i> on ischemic stroke, the anti-ischemic stroke activities of various crude extracts and derived compounds were evaluated using both middle cerebral artery occlusion/reperfusion (...

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Detalhes bibliográficos
Autor principal: Yan-Ping Zhang (432349) (author)
Outros Autores: Ling Li (38566) (author), Qian-Qian Yin (453477) (author), Ye-Wen Jia (22683815) (author), Ming-Xia Fang (21340067) (author), Qing-Qi Meng (21340070) (author), Yue Hou (2562085) (author), Jin-Le Hao (22683818) (author), Bin Lin (302181) (author), Di Zhou (126052) (author), Ning Li (45258) (author)
Publicado em: 2025
Assuntos:
Biochemistry
Medicine
Cell Biology
Pharmacology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
various crude extracts
significant antineuroinflammatory activity
potently inhibited lps
performance liquid chromatography
induced nitric oxide
ethyl acetate extract
electronic circular dichroism
alleviated cerebral edema
>] furan backbone
21 ± 3
04 ± 1
nmr ), high
potential biosynthetic pathways
characterized using high
aglaia perviridis </
6 </ b
5 </ b
1 </ b
ischemic stroke activities
contains total flavaglines
comprehensive phytochemical analysis
50 </ sub
2 microglia models
ms ), acd
2 </ b
perviridis </
b </
ischemic stroke
ape ),
therapeutic potential
rat models
evaluated using
2 cells
therapeutic effects
structure elucidator
probability analysis
mechanisms underlying
material basis
hplc ).
characteristic flavaglines
benz [<
ape led
10 μm
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