TEM-135 increases the MIC.

TEM-135 increases the MIC.

<p>(A) Penicillin G MICs of p<i>bla</i> variants in FA1090 isogenic strain background (one-way ANOVA on log<sub>2</sub>-transformed MIC values with Tukey multiple comparisons of means; *** p < 0.001). (B) MICs of TEM-1 in different p<i>bla</i> variant bac...

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Bibliographic Details
Main Author: Tabea A. Elsener (21253459) (author)
Other Authors: Ana Cehovin (499929) (author), Connor Philp (21253462) (author), Kate Fortney (21370578) (author), Stanely M. Spinola (21253468) (author), Martin C. J. Maiden (8174226) (author), Christoph M. Tang (8616405) (author)
Published: 2025
Subjects:
Microbiology
Molecular Biology
Biotechnology
Evolutionary Biology
Ecology
Infectious Diseases
Virology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
third generation cephalosporins
priority amr pathogen
mitigate fitness costs
neisseria gonorrhoeae </
haemophilus ducreyi </
sexually transmitted infection
confer increased resistance
three major p
extended spectrum beta
bla </
gonococcal infection
mediated resistance
increases resistance
widespread use
tetracycline therapy
public health
preventive strategies
mediated esbl
leading cause
gonococcal population
gonococcal beta
exposure prophylaxis
esbl ).
ending penicillin
current therapeutic
close relationship
certain p
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