Figure 4 from Preclinical Characterization of XB010: A Novel Antibody–Drug Conjugate for the Treatment of Solid Tumors that Targets Tumor-Associated Antigen 5T4

Figure 4 from Preclinical Characterization of XB010: A Novel Antibody–Drug Conjugate for the Treatment of Solid Tumors that Targets Tumor-Associated Antigen 5T4

<p>Combinatorial efficacy for XB010 and anti–PD-1 checkpoint inhibitor in a mouse syngeneic MC38-h5T4 model. Combination of XB010 and anti–PD-1 reagent enhanced antitumor activity (<b>A</b>) and improved survival (<b>B</b>) compared with either agent administered alone....

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Dettagli Bibliografici
Autore principale: Brian A. Mendelsohn (20667883) (author)
Altri autori: Kathleen R. Gogas (22762021) (author), Jeffrey N. Higaki (22762024) (author), Willy A. Solis (22762027) (author), Inna Vainshtein (20667877) (author), Jackie Cheng (20667880) (author), Minjong Park (22762030) (author), Marlene A. Hennessy (22762033) (author), Christine M. Janson (22762036) (author), Yutaka Matsuda (22762039) (author), Robyn M. Barfield (15087036) (author), Penelope M. Drake (22762042) (author), Stepan Chuprakov (22762045) (author), Colin L. Hickle (22762048) (author), Tom Linz (22762051) (author), Maxine Bauzon (22762054) (author), Dominick Y. Yeo (22762057) (author), Fangjiu Zhang (22762060) (author), Ayodele O. Ogunkoya (22762063) (author), Seema Kantak (20667862) (author)
Pubblicazione: 2025
Soggetti:
Cancer
Therapeutic Research and Development
Methods and Technology
Biological Agents & Therapies
Antibody-drug conjugates
Preclinical Models
In vitro models of cancer
Xenograft models
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