Effect of AUT00201 (1 µM) on PV properties after adult demyelination.

<p><b>A–E.</b> Bath application of AUT00201 (1 µM) had no significant effect on any of the intrinsic properties of PV interneurons following adult demyelination. Summary data showing the averaged (± s.e.m) of the AP threshold (A), the rheobase (B), the AP half-width (C), the AHP (D...

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Bibliographic Details
Main Author:	Sara Hijazi (21656615) (author)
Other Authors:	Maria Pascual-García (22404301) (author), Yara Nabawi (22404304) (author), Steven A. Kushner (11187162) (author)
Published:	2025
Subjects:	Biochemistry Medicine Neuroscience Physiology Evolutionary Biology Ecology Developmental Biology Mental Health Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified frequency firing associated examine intrinsic properties cortical network activity highlighted axonal myelination pv interneuron properties pv interneuron firing critical neurodevelopmental period pv interneuron function critical period juvenile myelination pv interneurons remyelination period using whole temporal control sustain high substantial decrease specific currents significant effects prefrontal cortex precise function partially recovered neuronal physiology lasting impairments interneurons throughout inhibitory transmission important factor feature implicated data uncovers cuprizone model common feature clamp recordings cerebral cortex cell patch 5 weeks
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Effect of AUT00201 (1 µM) on PV properties after adult demyelination.

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