Viral transcript production in EBOV- and MARV-infected HCOs at 1 and 3days post-infection.

Loess-smoothed plots showing the relative abundance of viral transcripts in human colonic organoids (HCOs) infected with EBOV or MARV compared to mock-infected controls at 1 and 3dpi. (A) EBOV-infected versus mock-infected HCOs. (B) MARV-infected versus...

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Autore principale:	Elizabeth Y. Flores (22676699) (author)
Altri autori:	Adam J. Hume (6107039) (author), Judith Olejnik (367849) (author), Aditya Mithal (22676702) (author), Andrew D’Amico (2248762) (author), MengWei Yang (22676705) (author), Pushpinder Bawa (733756) (author), Feiya Wang (21075016) (author), Aoife K. O’Connell (15462382) (author), Anna Tseng (20843165) (author), Nicholas A. Crossland (5500244) (author), Gustavo Mostoslavsky (110612) (author), Elke Mühlberger (45516) (author)
Pubblicazione:	2025
Soggetti:	Biochemistry Microbiology Cell Biology Genetics Molecular Biology Physiology Biotechnology Immunology Cancer Mental Health Infectious Diseases Plant Biology Virology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified xlink "> gastrointestinal support viral replication providing mechanistic insight induced secretory diarrhea colonic epithelial responses model ebola virus mediated ion transport human gi pathology ion transport severe diarrhea human ipsc stimulated genes specific induction powerful system pathogen interactions marburg virus junctional disruption including apical filovirus disease filoviral disease dissect host delayed virus colonic organoids central contributor
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Viral transcript production in EBOV- and MARV-infected HCOs at 1 and 3days post-infection.

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