<b>Dual </b><b>C</b><b>haracter of </b><b>S</b><b>urface </b><b>E</b><b>ngineering on SN38 </b><b>P</b><b>rodrug </b><b>N</b><b>ano-assemblies: </b><b>D</b><b>ivergent </b><b>E</b><b>ffects on </b><b>I</b><b>n </b><b>V</b><b>itro</b><b> </b><b>and </b><b>I</b><b>n </b><b>V</b><b>ivo</b><b> </b><b>B</b><b>ehavior</b>
<p dir="ltr">Nanoparticles formed at all PEGylation levels. Notably, the 80% NPs showed excellent stability, cytotoxicity, and cellular uptake but were also quickly cleared by the mononuclear phagocyte system (MPS) in vivo, causing SN38 leakage and intestinal toxicity. In comparison,...
Wedi'i Gadw mewn:
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| Cyhoeddwyd: |
2025
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| Pynciau: | |
| Tagiau: |
Ychwanegu Tag
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