Pharmacological inhibition of AMPAR improves social behaviors in <i>Mdga2</i> <sup>+/−</sup> mice.

Pharmacological inhibition of AMPAR improves social behaviors in <i>Mdga2</i> <sup>+/−</sup> mice.

<p>(<b>A</b>, <b>B</b>) The miniature inhibitory postsynaptic currents (mIPSCs) of hippocampal neurons in treated Het mice and their wild-type (WT) littermates were recorded and their kinetics (rise time and decay) were quantified for comparison. <i>n</i> =...

Full description

Saved in:

Bibliographic Details
Main Author:	Dongdong Zhao (1681897) (author)
Other Authors:	Yuanhui Huo (9698378) (author), Naizhen Zheng (9571988) (author), Xiang Zhu (135451) (author), Dingting Yang (20978386) (author), Yunqiang Zhou (9741770) (author), Shengya Wang (3162066) (author), Yiru Jiang (11083545) (author), Yili Wu (436485) (author), Yun-wu Zhang (478944) (author)
Published:	2025
Subjects:	Biochemistry Medicine Cell Biology Genetics Molecular Biology Neuroscience Science Policy Mental Health Biological Sciences not elsewhere classified tyrosine kinase b small molecular compound isoxazole propionic acid div >< p detailed physiological function dependent mechanism underlying synaptic function regulation excitatory synaptic suppressor derived neurotrophic factor autism spectrum disorder trkb signaling activity relevant synaptic underlies autism derived peptide trkb signaling signaling activation thereby competing therapeutic target social deficits results highlight may become like behaviors deficiency leads behavioral changes aberrant activation
Tags:	Add Tag No Tags, Be the first to tag this record!