Punctate white matter lesions are common in Fabry and controls.

<p>FLAIR axial images from Fabry and age/sex-matched controls are shown for three younger (top panel) and three older (bottom panel) participants. Overall, images were largely normal in both cohorts. Punctate WMLs in both Fabry and controls are identified (yellow arrowheads). In one Fabry pati...

Full description

Saved in:

Bibliographic Details
Main Author:	Jacob W. Johnson (20172850) (author)
Other Authors:	Hediyeh Baradaran (9861244) (author), Jubel Morgan (476471) (author), Henrik Odèen (22633876) (author), Emma Friel (22633879) (author), Carrie Bailey (7009100) (author), Brandon A. Zielinski (17051076) (author), Hunter R. Underhill (3151677) (author)
Published:	2025
Subjects:	Medicine Cell Biology Neuroscience Physiology Developmental Biology Mental Health Biological Sciences not elsewhere classified wml severity increased identify factors unique g ., fluid flair ), semi enzyme replacement therapy diffusion tensor imaging corpus callosum atrophied causes glycolipid accumulation became statistically significant attenuated inversion recovery 8 – 63 serial cognitive assessments progressive tissue damage common neurologic sequelae typical brain aging related brain alterations related cognitive decline older fabry patients white matter lesions median age 36 matched healthy controls div >< p using quantitative mri used structural mri younger fabry participants cognitive decline white matter quantitative mri structural mris participants underwent neurologic diseases microstructural damage mri study mri ). fabry drives fabry disease compared fabry rare x phenomena absent p </ normal age neuroradiologist ’ neurocognitive assessment lysosomal alpha linked deficiency large population insidious degeneration impaired cognition highly prevalent fisher ’
Tags:	Add Tag No Tags, Be the first to tag this record!

Punctate white matter lesions are common in Fabry and controls.

Similar Items