Panel showing radial MVMR plots corresponding to each of the simulated analyses presented in Table 1.

<p>Fig a represents the two-exposure model, while Fig b includes all measured exposures. Fig c, shows a plot generated after pruning pleiotropic SNPs identified in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011506#pgen.1011506.g004" target="_b...

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Bibliographic Details
Main Author:	Wes Spiller (13229484) (author)
Other Authors:	Jack Bowden (3452474) (author), Eleanor Sanderson (8611296) (author)
Published:	2024
Subjects:	Medicine Genetics Molecular Biology Biotechnology Infectious Diseases Virology Mathematical Sciences not elsewhere classified rmvmr r package coronary heart disease tools incorporated within may violate one give outlying estimates potentially pleiotropic variants outlier removal decreases multiple exposures simulatiously core iv assumptions pleiotropic genetic variants radial mvmr approach apply radial mvmr estimate causal effects genetic variants radial mvmr violating one outlying snps exposure within estimated effects radial plots radial formulation mvmr analysis mvmr analyses xlink "> various forms underlying assumptions unavailable due single exposure simulated examples often considered multidimensional nature lipid fractions instrumental variables important features help identify explored using chd ). applied analyses analogous plots accompanying software
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Panel showing radial MVMR plots corresponding to each of the simulated analyses presented in Table 1.

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