IFA effectively limited bacterial dissemination and protected mice from lethal hypervirulent K. pneumoniae pneumonia.

(A) Survival of mice 72 hours after K. pneumoniae infection. Mice were subcutaneously injected with 50 mg/kg IFA in 50 μl of 10% DMSO containing vehicle (10% DMSO, 45% stroke-physiological saline solution, 40% PEG400 and 5% Tween-80) or an equal volume...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Tingting Wang (123983) (author)
مؤلفون آخرون:	Huaizhi Yang (20513816) (author), Qiushuang Sheng (11577955) (author), Ying Ding (152708) (author), Jian Zhang (1682) (author), Feng Chen (25347) (author), Jianfeng Wang (232744) (author), Lei Song (30203) (author), Xuming Deng (158166) (author)
منشور في:	2025
الموضوعات:	Medicine Microbiology Pharmacology Biotechnology Cancer Infectious Diseases Virology Space Science Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified traditional herbal medicines mediated bacterial killing limited bacterial dissemination innovative alternative therapeutics identified isoferulic acid essential virulence determinant div >< p associated hypermucoviscosity phenotype promising candidate ifa attractive drug target lethal hvkp infection curb hvkp infection klebsiella pneumoniae </ hvkp infection pneumoniae </ ifa ), particularly drug k </ drug resistance hvkp ). work promotes urgently needed thus represents survival rate significant improvement resistant lineages potent broad major cause line antibiotics impaired hypercapsule high pathogenicity epidemic success enhanced pathogenicity energy status decreasing efficacy clinical settings alarming threat
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IFA effectively limited bacterial dissemination and protected mice from lethal hypervirulent <i>K</i>. <i>pneumoniae</i> pneumonia.

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